منابع مشابه
Autonomic innervation, atrial electrogram morphology, and atrial fibrillation.
everal lines of evidence suggest that autonomic innervation lays a role in the generation of atrial fibrillation (AF). anglionated plexi (GPs) that modulate autonomic inneration have been identified over both atria, particularly the ulmonary vein (PV) antral regions. Stimulation of GPs esults in the local release of parasympathetic and sympahetic neurotransmitters, which may lead to increased a...
متن کاملAutonomic cardiac innervation
Autonomic cardiac neurons have a common origin in the neural crest but undergo distinct developmental differentiation as they mature toward their adult phenotype. Progenitor cells respond to repulsive cues during migration, followed by differentiation cues from paracrine sources that promote neurochemistry and differentiation. When autonomic axons start to innervate cardiac tissue, neurotrophic...
متن کاملAutonomic Innervation of Heart
T he vagus and sympathetic nerves link the heart to the central nervous system, carrying information from the heart over neural afferents and to the heart over neural efferents. Although it is generally well accepted that the autonomic nervous system can promote, precipitate, or prevent the development of cardiac arrhythmias, the mechanisms by which this transpires are incompletely understood. ...
متن کاملAutonomic innervation of the heart.
This brief review describes recent advances in the areas of myocardial receptors that discharge into nonmyelinated, afferent, vagal C-fibers and the regional distribution of sympathetic postganglionic neurons to the myocardium. Complex, nonencapsulated nerve endings discharging into myelinated afferents have been known to exist for many years. More recently, however, indirect evidence for the e...
متن کاملLocal innervation and atrial fibrillation.
A trial fibrillation (AF) is the most common human arrhythmia in the world and, depending on individual demographics, afflicts from 0.1% to 4% of the general population. 1 With the steady rise of cardiovascular disease in the industrialized world, it is no surprise that the incidence of AF is also increasing. 2,3 However, despite its ubiquitous presence in adult medicine, AF remains an enigmati...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2014
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2013.09.020